Nutropin AQ 30iu Pre Mixed 10mg 2ml 1 pen box - High Quality For Bodybuilding - Top Jintropin Online Shop (2022)

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  • Nutropin [somatropin (rDNA origin) for injection] is a human growth hormone (hGH) produced by recombinant DNA technology. Nutropin has 191 amino acid residues and a molecular weight of 22,125 daltons. The amino acid sequence of the product is identical to that of pituitary-derived hGH. Nutropin may contain not more than fifteen percent deamidated GH at expiration. The deamidated form of GH has been extensively characterized and has been shown to be safe and fully active.
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  • Nutropin AQ 30iu Pre Mixed 10mg 2ml 1 pen box - High Quality For Bodybuilding - Top Jintropin Online Shop (3)
  • Nutropin AQ 30iu Pre Mixed 10mg 2ml 1 pen box - High Quality For Bodybuilding - Top Jintropin Online Shop (4)

Categories: HGH, , Hot Sell Product Tag: Nutropin

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Description

What’s Nutropin?

Nutropin [somatropin (rDNA origin) for injection] is a human growth hormone (hGH) produced by recombinant DNA technology. Nutropin has 191 amino acid residues and a molecular weight of 22,125 daltons. The amino acid sequence of the product is identical to that of pituitary-derived hGH. Nutropin may contain not more than fifteen percent deamidated GH at expiration. The deamidated form of GH has been extensively characterized and has been shown to be safe and fully active.

Whats Nutropin package in market ?

Nutropin is a sterile, white lyophilized powder intended for subcutaneous administration after reconstitution with Bacteriostatic Water for Injection, USP (benzyl alcohol preserved). The reconstituted product is nearly isotonic at a concentration of 5 mg/mL GH and has a pH of approximately 7.4.

Each 10 mg Nutropin vial contains 10 mg (approximately 30 IU) somatropin, lyophilized with 90 mg mannitol, 3.4 mg sodium phosphates (0.8 mg sodium phosphate monobasic and 2.6 mg sodium phosphate dibasic), and 3.4 mg glycine.

Bacteriostatic Water for Injection, USP is sterile water containing 0.9 percent benzyl alcohol per mL as an antimicrobial preservative packaged in a multidose vial. The diluent pH is 4.5 – 7.0.

Nutropin INDICATIONS

Pediatric Patients Growth Hormone Deficiency (GHD)
Nutropin® is indicated for the treatment of pediatric patients who have growth failure due to inadequate secretion of endogenous growth hormone (GH).
Growth Failure Secondary to Chronic Kidney Disease (CKD) Nutropin is indicated for the treatment of growth failure associated with CKD up to the time of renal transplantation. Nutropintherapy should be used in conjunction with optimal management of CKD.
Idiopathic Short Stature (ISS) Nutropin is indicated for the treatment of ISS, also called non-GHD short stature, defined by height SDS ≤-2.25, and associated with growth rates unlikely to permit attainment of adult height in the normal range, in pediatric patients whose epiphyses are not closed and for whom diagnostic evaluation excludes other causes associated with short stature that should be observed or treated by other means.
Short Stature Associated with Turner Syndrome (TS) Nutropin is indicated for the treatment of short stature associated with TS.
Adult Patients Nutropin is indicated for the replacement of endogenous GH in adults with GHD who meet eitherof the following two criteria:
Childhood Onset Patients who were GH deficient during childhood as a result of congenital, genetic, acquired, or idiopathic causes.
Adult Onset Patients who have GHD, either alone or associated with multiple hormone deficiencies (hypopituitarism), as a result of pituitary disease, hypothalamic disease, surgery, radiation therapy, or trauma,or idiopathic causes.

Patients who were treated with somatropin for GHD in childhood and whose epiphyses are closed should be reevaluated before continuation of somatropin therapy at the reduced dose level recommended for GH deficient adults. According to current standards, confirmation of the diagnosis of adult GHD in both groups involves an appropriate GH provocative test with two exceptions: (1) patients with multiple pituitary hormone deficiencies due to organic disease; and (2) patients with congenital/genetic GHD.

Nutropin AQ DOSAGE AND ADMINISTRATION For subcutaneous injection.

Therapy with Nutropin should be supervised by a physician who is experienced in the diagnosisand management of pediatric patients with short stature associated with growth hormone deficiency(GHD), chronic kidney disease, Turner syndrome, idiopathic short stature, or adult patients with either childhood-onset or adult-onset GHD.

Dosing for Pediatric Patients Nutropin dosage and administration schedule should be individualized for each patient. Response to growth hormone (GH) therapy in pediatric patients tends to decrease with time. However, in pediatric patients failure to increase growth rate, particularly during the first year of therapy, suggests the need for close assessment of compliance and evaluation of other causes of growth failure, such as hypothyroidism, under-nutrition, advanced bone age and antibodies to recombinant human GH (rhGH).

Treatment with Nutropin for short stature should be discontinued when the epiphyses are fused.

Pediatric Growth Hormone Deficiency (GHD) A weekly dosage of up to 0.3 mg/kg of body weight divided into daily subcutaneous injection is recommended. In pubertal patients, a weekly dosage of up to 0.7 mg/kg divided daily may be used.
Growth Failure Secondary to Chronic Kidney Disease (CKD) A weekly dosage of up to 0.35 mg/kg of body weight divided into daily subcutaneous injection is recommended.

Nutropin therapy may be continued up to the time of renal transplantation.

In order to optimize therapy for patients who require dialysis, the following guidelines for injection schedule are recommended:

Hemodialysis patients should receive their injection at night just prior to going to sleep or at least3 to 4 hours after their hemodialysis to prevent hematoma formation due to the heparin.
Chronic Cycling Peritoneal Dialysis (CCPD) patients should receive their injection in the morning after they have completed dialysis.
Chronic Ambulatory Peritoneal Dialysis (CAPD) patients should receive their injection in the evening at the time of the overnight exchange.
Idiopathic Short Stature (ISS)
A weekly dosage of up to 0.3 mg/kg of body weight divided into daily subcutaneous injections is recommended.
Short Stature Associated with Turner Syndrome (TS) A weekly dosage of up to 0.375 mg/kg of body weight divided into equal doses 3 to 7 times per week by subcutaneous injection is recommended.
Dosing for Adult Patients
Adult Growth Hormone Deficiency (GHD)
Either of two approaches to Nutropin dosing may be followed: a weight-based regimen or a non weight-based regimen.
Weight based Based on the dosing regimen used in the original adult GHD registration trials, the recommended dosage at the start of treatment is not more than 0.006 mg/kg daily. The dose may be increased according to individual patient requirements to a maximum of 0.025 mg/kg daily inpatients ≤35 years and to a maximum of 0.0125 mg/kg daily in patients over 35 years old. Clinical response, side effects, and determination of age- and gender-adjusted serum insulin-like growth factor (IGF-1) concentrations should be used as guidance in dose titration.
Non-weight based Alternatively, taking into account the published literature, a starting dose of approximately 0.2 mg/day (range, 0.15 to 0.30 mg/day) may be used without consideration of bodyweight. This dose can be increased gradually every 1 to 2 months by increments of approximately 0.1 to 0.2 mg/day, according to individual patient requirements based on the clinical response and serum IGF-1 concentrations. The dose should be decreased as necessary on the basis of adverse events and/or serum IGF-1 concentrations above the age- and gender-specific normal range.
Maintenance dosages vary considerably from person to person, and between male and female patients. A lower starting dose and smaller dose increments should be considered for older patients, who are more prone to the adverse effects of somatropin than younger individuals. In addition, obese individuals are more likely to manifest adverse effects, when treated with a weight-based regimen.
In order to reach the defined treatment goal, estrogen-replete women may need higher doses than men. Oral estrogen administration may increase the dose requirements in women.

Nutropin AQ SIDE EFFECTS

the most seriousa SIDE EFFECTS most frequently observedb adverse reactions during treatment with somatropin
Sudden death in pediatric patients with Prader-Willi syndrome (PWS) with risk factors includingsevere obesity, history of upper airway obstruction or sleep apnea and unidentified respiratoryinfection [see CONTRAINDICATIONS and WARNINGS AND PRECAUTIONS]. Intracranial hypertension [see WARNINGS AND PRECAUTIONS].
Intracranial tumors, in particular meningiomas, in teenagers/young adults treated with radiationto the head as children for a first neoplasm and somatropin [see CONTRAINDICATIONS and WARNINGS AND PRECAUTIONS]. Significant diabetic retinopathy [see CONTRAINDICATIONS].
[see WARNINGS AND PRECAUTIONS] Slipped capital femoral epiphysis in pediatric patients [see WARNINGS AND PRECAUTIONS].
Glucose intolerance including impaired glucose tolerance/impaired fasting glucose as well asovert diabetes mellitus [see WARNINGS AND PRECAUTIONS]. Progression of preexisting scoliosis in pediatric patients [see WARNINGS AND PRECAUTIONS].
Fluid retention manifested by edema, arthralgia, myalgia, nerve compression syndromes including carpal tunnel syndrome/paraesthesias [see WARNINGS AND PRECAUTIONS].
Unmasking of latent central hypothyroidism [see WARNINGS AND PRECAUTIONS].
Injection site reactions/rashes and lipoatrophy (as well as rare generalized hypersensitivity reactions) [see WARNINGS AND PRECAUTIONS].

Protocol-Defined Targeted Adverse Events in the ISS NCGS Cohort

Nutropin AQ 30iu Pre Mixed 10mg 2ml 1 pen box - High Quality For Bodybuilding - Top Jintropin Online Shop (5)

In subjects treated in a long-term study of Nutropin for ISS, mean fasting and postprandial insulin levels increased, while mean fasting and postprandial glucose levels remained unchanged. Mean hemoglobin A1c (A1C) levels rose slightly from baseline as expected during adolescence; sporadic values outside normal limits occurred transiently.

Adult Patients
Growth Hormone Deficiency
In clinical studies with Nutropin in GHD adults, edema or peripheral edema was reported in 41% of GH-treated patients and 25% of placebo-treated patients. In GHD adults, arthralgias and other joint disorders were reported in 27% of GH-treated patients and 15% of placebo-treated patients.

Nutropin therapy in adults with GHD of adult-onset was associated with an increase of median fasting insulin level in the Nutropin 0.0125 mg/kg/day group from 9.0 μU/mL at baseline to 13.0 μU/mL at Month 12 with a return to the baseline median level after a 3-week post-washout period of GH therapy. In the placebo group there was no change from 8.0 μU/mL at baseline to Month 12, and after the post-washout period, the median level was 9.0 μU/mL. The between-treatment group difference on the change from baseline to Month 12 in median fasting insulin level was significant, p < 0.0001. In childhood-onset subjects, there was an increase of median fasting insulin level in the Nutropin 0.025 mg/kg/day group from 11.0 μU/mL at baseline to 20.0 μU/mL at Month 12, in the Nutropin 0.0125 mg/kg/day group from 8.5 μU/mL to 11.0 μU/mL, and in the placebo group from 7.0 μU/mL to 8.0 μU/mL. The between-treatment group differences for these changes were significant, p = 0.0007.

In subjects with adult-onset GHD, there were no between-treatment group differences on change from baseline to Month 12 in mean A1C level, p = 0.08. In childhood-onset GHD, the mean A1C level increased in the Nutropin 0.025 mg/kg/day group from 5.2% at baseline to 5.5% at Month 12, and did not change in the Nutropin 0.0125 mg/kg/day group from 5.1% at baseline or in the placebo group from 5.3% at baseline. The between-treatment group differences were significant, p = 0.009.

Storage and Handling

Before Reconstitution – Nutropin and Bacteriostatic Water for Injection, USP (benzyl alcohol preserved), must be stored at 2-8°C/36-46°F (under refrigeration). Avoid freezing the vials of Nutropin and Bacteriostatic Water for Injection, USP (benzyl alcohol preserved). Expiration dates are stated on the labels.

After Reconstitution – Vial contents are stable for 14 days when reconstituted with Bacteriostatic Water for Injection, USP (benzyl alcohol preserved), and stored at 2-8°C/36-46°F (under refrigeration). Avoid freezing the reconstituted vial of Nutropin and Bacteriostatic Water for Injection, USP (benzyl alcohol preserved).

When reconstituting with Sterile Water for Injection, USP, use only one dose per Nutropin vial and discard the unused portion.

FAQs

What is Nutropin AQ used for? ›

Doctors prescribe Nutropin therapy for adults who have growth hormone deficiency that began either in: Adulthood as a result of pituitary disease, diseases of the hypothalamus, surgery, radiation therapy, or trauma; or. Childhood.

Is nutropin the same as somatropin? ›

Nutropin AQ® (somatropin) injection for subcutaneous use is a human growth hormone that is available by prescription only. Doctors prescribe Nutropin therapy for children and teenagers who are short or growing slowly because they: Do not make enough growth hormone on their own.

Where do you inject nutropin? ›

Injection sites, which may be located on the thigh, upper arm, abdomen or buttock, should always be rotated to avoid lipoatrophy. The Nutropin AQ Pen 10 and 20 mg Cartridges are color-banded to help ensure appropriate use with the Nutropin AQ Pen delivery device.

How do you use somatropin? ›

The usual dose is 0.06 mg per kg of body weight, given 3 times per week and injected under the skin or into a muscle. Your doctor may adjust your dose if needed.

What are 2 side effects of HGH? ›

The use of synthetic hGH for medical treatment can cause certain side effects including:
  • Carpal tunnel syndrome.
  • Increased insulin resistance and/or Type 2 diabetes.
  • Swelling in your arms and legs (edema).
  • Joint and muscle pain.
  • Enlargement of breast tissue (gynecomastia) in people assigned male at birth.
21 Jun 2022

How long does it take for HGH injections to start working? ›

Expected Results with Six Months of HGH Peptide Therapy

While patients will notice some significant increases changes in the body after the first month, the full-benefits are usually fully noticed after three to six months of therapy.

What happens when you stop taking growth hormone? ›

Psychological symptoms of GH withdrawal, reported in interviews at end-point by placebo-treated patients, included decreased energy, and increased tiredness, pain, irritability and depression.

How much does nutropin cost without insurance? ›

The cost for Nutropin AQ subcutaneous solution (5 mg/2 mL) is around $671 for a supply of 2 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
...
Subcutaneous Solution.
QuantityPer unitPrice
2 milliliters$666.75$1,333.49

What brand of growth hormone is best? ›

Here are the best HGH supplements:
  • HGH X2 Crazybulk – Overall the best HGH Supplement on the market.
  • GenF20 Plus – Best for Anti Aging supplement for Men.
  • HyperGH 14X – Best alternative to somatropin injections.
  • Provacyl – Best overall Anti Aging supplement for Wome.

How many times a week should you inject HGH? ›

The usual dose is 0.024 to 0.034 mg per kg (0.011 to 0.015 mg per pound of body weight) injected under the skin, on 6 to 7 days a week.

What happens if you inject too much HGH? ›

High levels of human growth hormone over a long period can produce irreversible acromegaly, but even smaller doses can lead to complications such as heart disease and diabetes. And because these hormones must be taken as injections, there are further administration risks such as a blood clot or dose error.

Can you inject HGH twice a day? ›

Conclusions: Twice-daily GH injections, apart from producing a more physiological serum GH profile, were superior to one injection in increasing serum IGF-I and decreasing IGFBP-1 levels. Both of these changes tend to amplify the effects of the administered GH.

Does HGH grow hair faster? ›

HGH, in fact, promotes hair growth and prevents hair loss, while the loss of hair is because of deprivation of growth hormones. HGH stimulates the liver to produce IGF-1, which stimulates hair growth on your scalp, body, as well as facial hair in men.

Does HGH make you look younger? ›

There's little evidence to suggest HGH can help otherwise healthy adults regain youth and vitality. Alternatively, HGH treatments may increase the risk of other medical conditions. Experts recommend against using HGH to treat aging or age-related conditions.

How many IU of HGH do I need to build muscle? ›

HGH Dosages For Bodybuilding

4-8 IU for body recomposition, general fat loss, and muscle improvement; Up to 15 IU for extreme muscle growth and strength gains.

Does HGH make your face bigger? ›

Long-term use of HGH injections can cause a condition called acromegaly. Adults cannot grow taller by using the synthetic growth hormone. High doses will thicken the person's bones instead of lengthening them. People with acromegaly will experience an overgrowth of bones, particularly in the hands, feet, and face.

Does HGH cause liver damage? ›

Growth hormone improves liver health in patients with nonalcoholic fatty liver disease (NAFLD) by reducing liver fat and inflammation, according to a new study presented Tuesday, June 14 at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

Can HGH damage nerves? ›

Possible side effects of excess hGH injections include: carpal tunnel syndrome. nerve, muscle, or joint pain.

Should I inject HGH in the morning or night? ›

HGH injections should be given several hours after the last meal. Insulin is at its most critical function after eating. The body can maximize its effects by injecting HGH shortly before bed.

How many inches can HGH give you? ›

For short, healthy children, studies predict that growth hormone will deliver an extra 1 to 3 inches as an adult. And that's the average; other factors come into play.

How long should you wait to eat after injecting HGH? ›

No, it is not advisable to eat carbohydrate and sugar for at least 60 minutes after taking a growth hormone shot.

Are hGH gains permanent? ›

After a user discontinues steroids, loss of muscle size and, to some degree, strength, is often reported. Size and strength gains made during use of hGH are permanent.

At which age hGH stop working? ›

Growth hormone and IGF-1 levels peak during puberty, then gradually decline after the age of 30, but the normal pituitary never totally stops its production of hGH. Some investigators feel that diminished levels of hGH may not be a bad thing.

How long do hGH effects last? ›

The circulating half-life of hGH is relatively short half-life (20-30 minutes), while its biological half-life is much longer (9-17 hours) due to its indirect effects.

How much is a month supply of HGH? ›

You can expect to pay $1000 to $5000 a month for injectable HGH from a legitimate company. This depends on the size and potency of the dose needed.

How much does Norditropin cost without insurance? ›

How much does Norditropin FlexPro cost without insurance? The average retail cost of Norditropin FlexPro without health insurance is $912.72 per 1.5, 1.5ML of 5MG/1.5ML Solution Pen-injector though you can save using a SingleCare Norditropin FlexPro coupon to pay only $582.37.

Why was Nutropin Depot discontinued? ›

(Nasdaq: ALKS) today announced their decision to discontinue commercialization of Nutropin Depot(R) (somatropin (rDNA origin) for injectable suspension). The decision is based on the significant resources required by both companies to continue manufacturing and commercializing the product.

Which HGH is best for muscle growth? ›

HyperGH 14X is the best HGH supplement for men that want to build muscle, reduce body fat, and enjoy faster recovery times from workouts. For those reasons, HyperGH 14X is a popular choice among bodybuilders, athletes, and gym goers.

What is the best age to take growth hormone? ›

“For some diagnoses (e.g., Turner syndrome), earlier initiation of GH treatment is recommended (starting at ages 4 to 6 years old), especially if the child's growth failure is already evident. It is too late to start GH treatment once growth is complete and the child's growth plates are fused.”

Does HGH increase testosterone? ›

First, it's important to point out that HGH has very little—if any—impact on testosterone levels, as this particular protein is not involved in the production of testosterone. In the most literal sense, HGH is not an effective treatment for low testosterone.

Do height growth hormones work? ›

In one study that followed children throughout adolescence, girls treated with growth hormone reached heights of about three inches taller than an untreated control group by near-adulthood. In another study, children treated with growth hormone were 1.4 inches taller than children treated with an inactive placebo.

What medical conditions are treated with hGH? ›

Synthetic hGH is used to treat poor growth in children and adults. It can also be used to treat adults with short bowel syndrome or muscle loss due to HIV or AIDS. Lack of growth may be the result of medical causes such as: chronic kidney disease.

What does height growth hormone do? ›

The roles of growth hormone include influencing our height, and helping build our bones and muscles. Natural levels of growth hormone fluctuate during the day, seemingly influenced by physical activity. For example, levels rise when we exercise. Growth hormone levels increase during childhood and peak during puberty.

What type of drug is nutropin? ›

Nutropin AQ® injection for subcutaneous use is a human growth hormone that is available by prescription only. Doctors prescribe Nutropin therapy for children and teenagers who are short or growing slowly because they: Do not make enough growth hormone on their own.

At which age does a boy stop growing? ›

Changes in Boys

They tend to grow most quickly between ages 12 and 15. The growth spurt of boys is, on average, about 2 years later than that of girls. By age 16, most boys have stopped growing, but their muscles will continue to develop.

How many inches can HGH give you? ›

For short, healthy children, studies predict that growth hormone will deliver an extra 1 to 3 inches as an adult. And that's the average; other factors come into play.

Can I grow taller after 25? ›

An adult cannot increase their height after the growth plates close. However, there are plenty of ways a person can improve their posture to look taller.

Does HGH damage your liver? ›

Growth hormone improves liver health in patients with nonalcoholic fatty liver disease (NAFLD) by reducing liver fat and inflammation, according to a new study presented Tuesday, June 14 at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

What are 4 side effects of HGH? ›

HGH treatment might cause a number of side effects for healthy adults, including:
  • Carpal tunnel syndrome.
  • Increased insulin resistance.
  • Type 2 diabetes.
  • Swelling in the arms and legs (edema)
  • Joint and muscle pain.
  • For men, enlargement of breast tissue (gynecomastia)
  • Increased risk of certain cancers.

What happens when you stop taking HGH? ›

Psychological symptoms of GH withdrawal, reported in interviews at end-point by placebo-treated patients, included decreased energy, and increased tiredness, pain, irritability and depression.

How long do you take HGH for bodybuilding? ›

It is often taken in 4-6 week cycles and in combination with other performance-enhancing agents, especially anabolic steroids.

Does HGH increase testosterone? ›

First, it's important to point out that HGH has very little—if any—impact on testosterone levels, as this particular protein is not involved in the production of testosterone. In the most literal sense, HGH is not an effective treatment for low testosterone.

What is the best time to take growth hormone? ›

Time of Day
  • Give GH at night, preferably within an hour of sleep. ...
  • You may change the time occasionally, by a few hours earlier or later, but do not give before 5 p.m, except under unusual circumstances (such as leaving for a trip, a sleep-over, etc.)
  • Do not make up missed injections.

How much does nutropin cost without insurance? ›

The cost for Nutropin AQ subcutaneous solution (5 mg/2 mL) is around $671 for a supply of 2 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
...
Subcutaneous Solution.
QuantityPer unitPrice
2 milliliters$666.75$1,333.49

Is HGH harmful? ›

Unsafe use of human growth hormone

The illegal use of HGH without a prescription, for example to promote muscle growth, is risky. It can cause acromegaly, and possibly diabetes, high blood pressure, liver damage, heart problems and premature aging.

Should I take HGH for bodybuilding? ›

Although it may promote the growth of collagen tissues like tendon, ligament, and bone, for the bodybuilder or athlete looking for strength advantage, HGH has little to offer because any muscle enlargement is due to fluid retention. In addition, adverse effects can be significant.

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